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Index
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Anaphy & Physiology
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MUSCULAR SYSTEM
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Level 1 of MUSCULAR SYSTEM
level: Level 1 of MUSCULAR SYSTEM
Questions and Answers List
level questions: Level 1 of MUSCULAR SYSTEM
Question
Answer
What are the 3 types of Muscle?
Cardiac,Smooth,and Skeletal Muscle
This muscle is Long and cyndrical in shape its nucleus are multiple and peripherally located. Has striations and it is Voluntary.
Skeletal Muscle
This muscle is Spindle-Shaped and its nucleus is single,centrally located. There is no striations and it is involuntary.
Smooth Muscle
This muscle is branched and cylindrical in shape its nucleus is single and also centrally located. There is striations and it is involuntary.
Cardiac Muscle
Loose connective tissue seperates muscles fasciles from each other.
Permysium
Loose connective tissue surrounds each muscle fibers.
Endomysium
It is the cytoplasm of a muscle fiber. cytoplasm of muscle fiber (cell) • Has little RER or free ribosomes • Filled primarily of myofibrils • acidophilic
Sarcoplasm
Within the sacroplasm,each muscles fiber contains many bundles of proteins filaments called
Myofibrils
Myofibrils consist of 2 major kinds of proteins what are those?
Actin myofilaments and Myosin myofilaments.
It is the basic structural and fundamental unit of a skeletal muscle beacuse it it the smallest portion of a skeletal muscle capable of contacting.
Sacromeres
It is the cell membrane of the muscle fiber.
Sarcolemma
ability to shorten
Contractility
respond to stimulus
Excitability
can stretch
Extensibility
Ability of muscle to recoil
Elasticity
Skeletal muscle is surrounded by a connective tissue sheath called
Epimysium
• skeletal muscle cells • many nuclei
Muscle Fiber
proteins that make up myofibrils • Myosin II (thick filaments) • Actin (thin filaments) • + associated proteins
Myofilament
• Specialized for calcium ion sequestration • The depolarization of its membrane, which results to Ca2+ ions, is initiated at the specialized neuromuscular junction (NMJ) on the surface of the muscle cell
Sarcoplasmic reticulum
• Finger-like invaginations in the sarcolemma • Form a complex network of tubules that encircles every myofibril near the A-I band boundaries of each sarcomere • Provide uniform contraction
Transverse Tubule (T-tubule)
• Darker bands • More electron-dense • Composed mainly of thick filaments in addition to overlapping portions of thin filaments
A band
• Lighter bands • Consist of thin filaments that do not overlap with thick filaments
I band
• Narrow, less electron-dense (lighter zone) bisecting the A bands • A region consisting only of the rod-like portions of the myosin molecule with no thin filaments present
H zone
• Zwischenscheiben (Ger., between the disks) • A dark transverse line bisecting each I band
Z line or Z disk
• Thick filaments • contain two heavy chains: MYOSIN TAIL; • free ends of heavy chains + light chains: MYOSIN HEAD (binds to actin) • BODY: tails that are bundled together • CROSS-BRIDGES: arms and myosin heads • HINGES: arm-body and arm-head
Myosin
• Think filaments occupying the I bands • One end bound to α-actinin (major protein of Z disk)
Actin
• Covers the binding site (underwear)
Tropomyosin
• Responsible for the control Two minute strands pearls twisted together.
Troponin
attaches troponin complex to tropomyosin
Troponin T
Inhibits actin-myosin binding
TROPONIN I
calcium binding protein; displaces tropomyosin
Troponin C
• Largest protein in the body • Tethers myosin to Z lines (scaffolding) • Binds Z line to M line
Titin
• Attaches to plasmalemma • Stabilizes plasmalemma and prevents contraction-induced rupture
Dystrophin
Binds actin to Z lines
Actinin and CAPZ protein
Binds Z lines to plasma membrane
Desmin
• Myosin head is attaching to a new binding site • Myosin head is displaced toward the positive end of actin
Recocking
• Actin towards the negative pole
Power stroke=force
• “electricity” • stimulus that causes rapid depolarization and repolarization • causes muscle to contract
Action Potential
change in charges - inside becomes more + and outside more – - Na+ channels open
Depolarization
- Na+ channels close - change back to resting potential
Repolarization
- pumps Na+ out of cell and transports K+ into cell - restores balance
Sodium Potassium Pump
nerve cells that carry action potentials to muscle fibers
Motor neuron
where nerve cell and muscle fiber meet
Neuromuscular junction (synapse)
end of nerve cell (axon)
Presynaptic terminal
muscle fiber membrane
Postsynaptic membrane
space between presynpatic terminal and postsynaptic membrane
Synaptic Cleft
- in presynaptic terminal - store and release neurotransmitters
Synaptic Vesicles
- chemicals that stimulate or inhibit a muscle fiber - Ex. Acetylcholine
Neurotransmitter
group of muscle fibers that motor neuron stimulates
Motor unit
person dies and no ATP is available to release cross- bridges
Rigor mortis
Striations of skeletal and cardiac muscle are due to
sarcomeres (actin and myosin).
muscle contracts or doesn’t (no in between)
All or None Law
nonmovable end
Origin
movable end
Insertion
middle of the muscle
Belly
muscles that work together
Synergists
muscles that oppose each other
Antagonist
raises eyebrows (forehead)
Occipitofrontalis
allows blinking (eyes)
Orbicularis oculi
kissing muscle (mouth)
Orbicularis oris
smiling muscle (cheek)
Zygomaticus
chewing (mastication) muscle
Masseter
elevate ribs for inspiration
External intercostals
depress ribs during forced expiration
Internal intercostals
moves during quiet breathing
Diaphragm
- center of abdomen - compresses abdomen
Rectus abdominis
- sides of abdomen - compresses abdomen
External abdominal oblique
compresses abdomen
Internal abdominal oblique and Transverse Abdominis
- shoulders and upper back - extends neck and head
Trapezius
- chest - elevates ribs
Pectoralis major
between ribs - elevates ribs
Serratus anterior
- shoulder - abductor or upper limbs
Deltoid
- 3 heads - extends elbow
Triceps brachii
- “flexing muscle” - flexes elbow and shoulder
Biceps brachii
flexes elbow
Brachialis
- lower back - extends shoulder
Latissimus dorsi
4 thigh muscles
Quadriceps femoris
- front of thigh - extends knee and flexes hip
Rectus femoris
extends knee
Vastus lateralis,Vastus medialis and Vastus intermedius:
adducts thigh and flexes knee
Gracilis
- hamstring - back of thigh - flexes knee, rotates leg, extends hip
Biceps femoris, semimembranosus, semitendinosus
- front of lower leg - inverts foot
Tibialis anterior
- calf - flexes foot and leg
Gastrocnemius
- attaches to ankle - flexes foot
Soleus
What are the 4 functional groups of skeletal muscle?
Prime Movers,Antagonist,Synergists,Fixators
One of the Functional Groups of skeletal muscle that is responsible for adduction.
Prime movers
One of the Functional Groups of skeletal muscle that reverse the particular movement of prime movers. responsible for abduction.
Antagonists
One of the Functional Groups of skeletal muscle that helps the prime movers. Lending a little extra oomph and stabilizing joints against dislocation.
Synergist
Group of muscle fibers that all get their signals from the same,single motor neuron.
Motor Units
Motor neuron may synapse with & innervate,a thousand muscle fibers.
Large motor units
No matter how large or small,responds to a single action potential those fibers quickly contract and release,in what you call?
TWITCH
What are the three distict phases of twitch?
Latent Period,Period of contraction,Relaxation Period
What distict phases of twitch,when the stimulus arived,but no force is being produced.
Latent Period
What distict phases of twitch,when myosin head are binding,and pulling,and releasing,over and over,and the muscle fibers contract.
Period of Contraction
What distict phases of twitch,When the calcium gets pumped back into the sarcoplasmic reticulum,and the actin and myosin stop the binding cycle.
Relaxation Period
one muscle can produce a variation of smoooth forces. they're generally affected by both the frequency and strength with which they're stimulated.
Graded Muscle
twitches end up adding to each other as they get closer together in time,this happens when relaxation are being occur and anothenr contraction happens.
Temporal Summation
When all those little twitches blend together until they feel like one gigantic contraction.This is when you use all your force in contraction nonstop until you gets fatigue.
Tetanus