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level: A2 agonists and Alpha blockers

Questions and Answers List

level questions: A2 agonists and Alpha blockers

Question	Answer
A2 agonist drug given to pregnant patients with hypertension	Methyldopa
A discontinued drug that is related to guanfacine	Guanabenz
Given to patients with ADHD of 12 years old and below	Guanfacine
A2 agonist drugs given to patients with glaucoma	Apraclonidine, Brimonidine
Which A2 agonist does NOT cross the BBB?	Apraclonidine
Drug given to patients with ocular hypertension	Brimonidine
Drugs of the Imidazoline group besides Clonidine given for hypertension	Rilmenidine, Moxonidine
Effect of A1 blockade on blood vessels	Vasodilation
Which Alpha receptor should be blocked to alleviate BPH symptoms?	A1
Which Alpha receptor should be blocked to remove negative feedback?	A2
Which Alpha receptor should be blocked to facilitate insulin release	A2
Drug examples of reversible Alpha blockers	Prazosin, Tamsulosin, Phentolamine
Drug prototype for reversible Alpha blocker	Phentolamine
Reversible, non-selective Alpha blocker	Phentolamine
Major adverse effect of Phentolamine on CVS	Hypotension
Alpha blocker given to prepare surgical removal in Pheochromocytoma	Phenoxybenzamine
Alpha blocker given to during operative manipulation	Phentolamine
Alpha blocker given to reverse local anaesthesia	Phentolamine
Alpha blocker given during hypertensive crisis	Phentolamine
Alpha blocker given for Male Erectile Dysfunction	Phentolamine
Alpha blocker given for peripheral vascular diseases like Raynaud's Phenomenon and Burger's Disease	Phenoxybenzamine
Prototype of irreversible Alpha blockers	Phenoxybenzamine
Non-selective A1ABD blockers	Prazosin, Terazosin, Doxazosin
Selective A1A blockers	Tamsulosin, Alfuzosin, Silodosin
Which selective A1A blocker has the highest apoptotic effect?	Silodosin
Which A1 blockers are less likely to cause first dose effect and lipid profile changes?	Tamsulosin, Silodosin
Which selective A1 blocker may cause QT prolongation?	Alfuzosin
Which selective A1 blocker shoud not be given wih CYP3A4 inhibitors?	Alfuzosin
Which selective A1 blockers may cause abnormal ejaculation and Intraoperative Floppy Iris Syndrome?	Tamsulosin, Silodosin
Which A1 blockers are given to patients with hypertension AND patients with BPH?	Prazosin, Terazosin, Doxazosin
Which A1 blockers are given to patients with BPH only?	Alfuzosin, Tamsulosin, Silodosin
Which A1 blocker is given to patients with CHF?	Prazosin
Selective competitive A2 blocker	Yohimbine
Which drug is given to improve athletic performance and weight loss?	Yohimbine
Which drug should not be given to people with hypertension, angina, and renal impairment?	Yohimbine