SEARCH
You are in browse mode. You must login to use MEMORY

   Log in to start

level: Level 1

Questions and Answers List

level questions: Level 1

QuestionAnswer
what is first line treatment of hypertensionACE inhibitors
What is the mode of action of ACE inhibitors?Works in the RAAS system - ACE inhibitors works in the lungs by inhibiting the conversion of angiotensin I to angiotensin II which Reduces vasoconstriction and Decreases aldosterone secretion from the adrenal gland = loss of fluid and sodium in the urine
Side effects of ACE inhibitors?GI upset, persistent dry cough, dizziness, anemia, hyperkalaemia, hyponatraemia, angioedema
What is the mode of action of calcium channel blockers?Inhibit the movement of calcium ions across cell membranes of myocardium and arterial muscle cells (stops action potential- block heart muscle cell contraction, Depresses myocardial contractility, Relaxes and dilates arteries Decreases BP and venous return
Nursing considerations for ACE inhibitors?*Take 1 hour before or 2 hours after food *Teratogenic * Warn patient to avoid dehydration and excessive perspiration as it may lead to a greater fall in BP, increasing the risk of fainting, therefore patient should maintain hydration within prescribed limits *BP is recorded every 15 minutes for 1 hour after the initial dose and, if a hypotensive response occurs, place the patient in a supine position *NSAIDS react with medications
Side effects of calcium channel blockers?peripheral oedema, skin flushing, rash, liver damage, heart block
Nursing considerations for calcium channel blockers?*No grapefruit (increases serum levels) *Good oral hygiene - risk of gingiva hyperplasia *Swallow whole -dont crush or chew *Monitor blood pressure and pulse
What is the mode of action of thiazide diuretics?inhibit reabsorption of sodium and chloride at the beginning of the distal convoluted tubule which promotes excretion of water and sodium resulting in increased urinary volume
Side effects of thiazide diuretics?• GI irritation • Thirst • Polyuria • Electrolyte imbalances (hyponatremia and hypokalaemia). • Postural hypotension
Nursing considerations of diuretics?*Monitor for dehydration *Monitor renal function and electrolytes *take in the morning due to polyuria
What is the mode of action for Angiotensin 2 receptor blockers?Works in RAAS. Selectively binds to ACE 2 receptors sites in vascular smooth muscle and adrenal cortex. Blocks vasoconstriction and release of aldosterone which decreases blood pressure.
Side effects of ARBs?hypotension, dizziness, syncope, dry mouth, resp tract infections
Nursing considerations of ARBs?*Assess blood pressure and pulse routinely *Monitor potassium levels - hyperkalemia *Teratogenic - can cross placenta *Falls risk due to hypotension *Avoid potassium substitutes
What is the mode of action for beta blockers?Beta 1 adrenergic receptor blocker – blocks receptor sites in the myocardium preventing epinephrine from binding to receptors causing decrease heart rate, contractility and cardiac output and reduce the release of renin
What are the side effects of beta blockers?gi upset, dizziness, bradycardia, cold extremities, CNS effects
Nursing considerations for beta blockers?• Withheld less than 60bpm • advise to change positions slowly to prevent orthostatic hypotension * monitor blood glucose
What class is digoxin from?cardiac glycoside
what is digoxin used for?Heart failure and atrial fiblliration
What is the mode of action of digoxin?Inhibition of the sodium pump increases intracellular sodium and increases the calcium level in the myocardial cells causing an increased contractile force of the heart. indirect effect : Stimulates parasympathetic nz via vagus nerve-  leading to sinoatrial (SA) and atrioventricular (AV) node effects that decrease the heart rate
Nursing considerations for digoxin?*Not to be used in pregnancy *Pulse for 1 min before administering; hold dose if pulse < 60 *Retake pulse in 1 hr. If adult pulse remains < 60 hold drug and notify prescriber *Educate patient on signs of toxicity and – rehiterate the importance of blood tests *Avoid meds with meals- delays aborbtion
Mode of action of GTN?provide a source of nitric oxide which mediates relaxation of smooth muscle - widening blood vessels, letting more blood and oxygen reach your heart. This reduces strain on your heart, making it easier for your heart to pump blood.
Side effects of GTN?Headache Dizziness Hypotension nausea/vomitting
What are the symptom of right sided hear failure?Distended, pulsating neck vein (sit patient upright- more noticeable) Peripheral oedema – weight gain, swollen ankles/feet Hepatomegaly and splenomegaly(enlarged speen) (enlarged liver – size and weight due to fluid in abdomen Ascites (abdo fluid) Anorexia and GI upset Dyspnoea
What are 4 factors that cause cardiac arrest?*Myocardial infarction *hypovolemic shock(decreased volume of blood) * Hypoxia *Trauma
What are signs of cardiac arrest?*chest pain *SOB *fatigue *anxiety-impending sense of doom
how are deteriorating patients managed in hospital?*MET call *EWS score *emergency bells *Resuss trolley and defib
What does CPR stand for?cardio pulmonary resuscitation
What does CPR do for the heart?Chest compressions increase intrathoracic pressure and apply direct compression of the heart
Why do children most likely go into cardiac arrest?Because they are deprived of oxygen
What are the shockable rhythms?Ventricular fibrillation & ventricular tachycardia
What are the non shockable rhythms?Asystole & pulseless electrical activity
How much adrenaline is administered for anaphylaxis?0.3-0.5mL 1:1000 - Intramuscular into vastus lateral(side of thigh)
What is the goal from post resuscitation treatment?*assess ABCDE *treat causes *12 lead ECG *re-evaluate oxygenation and ventilation *temperature control
Risk factors associated with anesthesia?*Type of procedure *Age *Diabetes - impaired healing, electrolyte balance *Cardiac/resp disease *Cognitive/renal/hepatic function
What info is gathered in pre-op assessment to identify risk factors?*Medical history *Medications *Physical disabilities *Surgical/anesthetic history - PONV
What other things are considered in the pre-op assessment?*Cultural considerations *Emotional status *Baseline obs *Patient education *Post op support
What are the triad of medications used in general anesthetic?Hypnotic, analgesic and muscle relaxant
What are the three phases of GA?induction, maintenece, emergence
What are some physiological changes in surgery due to positioning?Skin - risk of pressure/sheer injuries or temp Resp system - Less room for lungs to expand – abdominal area shifts upwards – reduces inspiration and expiration Cardiovascular system - risk of DVT- anesthesia causes peripheral dilation lowers BP and causes blood to pool in areas
why is thermal support important intraoperatively?risk of hypothermia - agents provide vasodilation causing heat loss
identify and explain two medications that are risk factors intraoperatively ?Anticoagulants - alter normal clotting factors - risk of hemorrhaging. Discontinue at 48 hours before surgery Antihypertensive - beta-blockers and calcium channel blockers, interact with anesthetic agents to cause bradycardia, hypotension and impaired circulation
What is the aim of post op care?oxygenation circulation of blood comfort nutrition and fluids elimination movement and exercise hygiene psychological support protection and safety
What the goal of oxygenation in post op care?Assessment is also made of colour and breathing to observe for the signs of any respiratory tract complications. Mucus secretions can accumulate, leading to pneumonia, bronchitis or atelectasis.
What is the goal of circulation of blood in post op care?risk of DVT and pulmonary embolus. During this period deep breathing, coughing and, if possible, leg exercises and early ambulation are encouraged
What is the goal of elimination in post op care?It is important to observe urinary output on an ongoing basis. If retention of urine or inadequate emptying of the bladder occurs, it may be necessary for the individual to have a urinary catheter inserted
What is the goal of comfort in post op care?assume a semi-upright position. This position promotes adequate lung expansion, and assists urinary or wound drainage by gravity
What is the effects of pain in the post-op patient?• Enhances surgical stress response • Causes tachycardia & hypertension • O2 demand increases • Respiratory function compromised • Reduced ability to mobilise
Injured tissues release prostaglandins that stimulate the pain pathway to the cerebral cortex where pain is perceived. True or false?True
What is the nursing management of a post op hemorrhage?*Assess vital signs - cognition *Check wound dressing *Check estimated blood loss *Pain assessment *Blood tests (FBC + hemoglobin
What is the nursing management of hypotention/shock?*IV fluids, blood products *position patient flat *Assess causes
What is the nursing management of a post-op CVA?Assessment of hemiparesis, facial drooping, speech, orientation, LOC
What is the nursing management of post-op urinary retention?Usually normal after surgery - should pass urine within 6 hours *monitor fluid balance *encourage fluid intake *sit upright position for gravity *monitor weight *sound of running water *warm shower *bladder scan if nor successful *possible catheter
What is the nursing management for post op delirium?*check underlying causes - medications, dehydration, electrolyte imbalance *delirium assessment *close monitoring *re-orientate patient *falls risk *Promote safe environment
what is the nursing management of a post op pulmonary embolism?vital signs anticoagulant if needed mobilization TED stockings - calf pumps
what is the nursing management of hypoventilation?*monitor resp rate, depth and effort *check medication history *Sit patient upright *assess pain - remove restricting dressings *administer o2 if decreased o2 sats
what is the nursing management of post-op constipation?*Encourage fluids(kiwi crush) *mobility *manual evacuation *laxatives
what does hypersensitivity mean?An excessive or abnormal sensitivity to a substance. A person who is hypersensitive to a certain drug will often suffer a severe allergic reaction
what is hypersensitivity type 1?Also known as allergic reaction - Immediate reaction – IgE mediated response Occurs within minutes of exposure
what is the physiological effects of anaphylaxis?vasodilation - hypotension bronchoconstriction - reduced breathing - cyanosis increased heart rate fluid shift - reduced blood volume increased capillary permeability - swelling
Signs of anaphylaxis?*Swelling of the eyes and face *noisy breathing - wheeze or stridor *red raised rash *hypotension *tachycardia *stomach pain *loss of consciousness
what is the treatment of anaphylaxis?Adrenaline,O2, IV access, fluid replacement, antihistamines, hydrocortisone
why is adrenaline given in anaphylaxis?Prevents (or relieves) –laryngeal oedema, circulatory collapse, release of histamine and other mediators Provides bronchodilation (SYMPATHETIC)
how much adrenaline is used in anaphylaxis?0.5mLs - 1:1000
what is HIV?Type of retrovirus that attacks CD4 T helper cells which help the body fight off infections - therefore making a person with HIV more vulnerable to other infections (dendritic cells present virus to T cells)
what is a retrovirus?a type of virus that inserts a copy of its RNA into the DNA of a host cell - hijaks host cell and causes it to die and the retrovirus will move into surrounding cells
What are the symptoms of HIV?Flu like symptoms develop 2-4 weeks after exposure As the virus replicates patient remains symptom free as the body makes antibodies to try fight the infection further progression means the CD4 cell count is less than 200 which leads to aids defining conditions
what are aids defining conditions?classified as being directly associated with advanced HIV infection - presence of AIDS
what is the mode of action of NNRTIs (non-nucleoside reverse transcriptase inhibitors?Binds to and blocks HIV reverse transcriptase enzyme to prevent replication
what is the mode of action of integrase strand transfer inhibitors (INSTIs)?Inhibits the strand transfer step of retroviral DNA integration which is essential for HIV replication.
what is the mode of action of protease inhibitors?inhibits the action of protease enzyme preventing replication
what is the mode of action of the biologic medication 'infliximab?Binds to tumor necrosis factor inhibiting the inflammatory cascade which suppresses chronic inflammation and immune response activation. (TNF is high with autoimmune diseases )
How do DMARDs workwork to slowly modify autoimmune diseases by suppressing immune and inflammatory response - inhibit T & B cells
Why are injections used to administer medication?*Faster absorption time *Patients who are unable to swallow *Some meds are poorly absorbed in the GI tract *Patients who have fluid restrictions
Length of a needle is dependent on?IM or S/C Site Muscle mass Subcutaneous fat
importance of subcut injections?*Used for small volumes of medications *slow absorption time - not as many blood vessels *risk of lipohypertrophy -
importance of intramuscular injections?In the muscle layer Suitable for larger volumes than subcutaneous sites Faster absorption
Potential complications of IM injections?*Pain *Bleeding *Injury to nerves or blood vessels *Abscess
Common sites for IM injection?Deltoid Vastus lateralis – Side of thigh Rectus femoris – Not commonly used - front of thigh Ventrogluteal - side of hip Dorsogluteal - upper outer glute - not recommended due to sciatic nerve injury
skin is pulled while administering IM injection using a Z track technique to prevent medication going into the subcut tissue. True or false?True
What is the pathophysiology of lymphedema?collection of fluid that collects in the interstitial spaces of the arm or leg due to a blockage in the lymphatic system.
What causes lymphedema?*Removal of lymph nodes *Damage from cancer treatment *Trauma *Genetics
Signs and symptoms of lymphedema?*Swelling in affected limb *Soreness *Weakness
What are some things to consider post mastectomy with node removal ?*Physiotherapy - exercise - to help with drainage *Compression bandage
Things to avoid after surgery to reduce risk of lymphedema?*Injections/blood tests on the affected area - local inflammatory response *Vigorous lifting *Sunburn *Tight clothing on area
Education around post surgery to reduce risk of lymphedema?*Elevate arm when possible *healthy diet *prevent trauma *maintain skin care
What is Lymphadenopathy?Enlarged swollen lymph nodes
What causes Lymphadenopathy?Usually infection - elevated white blood cells
Tonsillitis is a cause of Lymphadenopathy, what are symptoms?*sore throat *swollen enlarged tonsils *fever *difficulty swallowing
what is the first line treatment for tonsillitis caused by bacteria(streptococcus)?Penicillin
What is Non-Hodgkin's lymphoma ?cancer of the lymphocytes in the lymphatic system without the presence of reed Sternberg cells - more common
What is Hodgkin's lymphoma?cancer of the lymphocytes WITH the presence of reed Sternberg cells
What is the symptoms of malignant lymphomas?*Enlarged lymph nodes *night sweats *fever *weight loss *fatigue
Nursing considerations for lymphomas?*Patient education *Psychological support *identify barriers
treatment of lymphomas?dependent on severity chemotherapy - most common radiation immunotherapy stem cell transplant
side effects of lymphoma treatment?chemo can damage bone marrow Anaemia (low hemoglobin) can cause shortness of breath, tachycardia, or fatigue Thrombocytopenia (low platelet count) puts patients at risk of bleeding or bruise Neutropenia (low white blood cell count) puts the patient at increased risk of infection Nausea and vomiting
What are some factors that hinder wound healing?Age - impaired venous return + decreased Langerhans cells genetics predisposing medical conditions (diabetes, renal disease) stress - affects immune system Nutrition- malnutrition will affect wound healing such as a protein deficiency Smoking- causes vasoconstriction which reduces the amount of oxygen available to the cells
What is a chronic wound?A wound that has remained unhealed for more than 4 - 6 weeks- pressure sore, diabetic wound, post-op wound
What mnemonic is used for wound assessmentHEIDI
what is involved in the examination part of HEIDI?Assess the peri-wound - measurement, infection, edema, pulse(circulation)
what is the goal of moisture in a wound?goal is to maintain moisture - not to dry or too wet - dressings correct this
what is the E part in TIME assessment?Edges - make sure not undermining and rolling
what is the investigations part of HEIDI?Investigations - do we need more investigations? checking pulses and sensations(monofilament pen), wound swap, tissue biopsy, xray
What are 4 responsibilities of the RN in the assessment and management of wounds?undertake appropriate monitoring select appropriate dressings complete and update wound care plans wound swabbing if directed
stages of pressure injuries?Stage 1 - non blanchable erythema stage 2 - partial thickness skin loss stage 3 - full thickness skin loss stage 4 - full thickness tissue loss with exsposed bone or muscle
what is SSKIN to manage and prevent pressure injuries?S: Surface - Make sure patients are on supportive surfaces S: Skin assessment – early inspection = early detection K: Keep moving – encourage mobilisation where appropriate I: Incontinence – individualised continence management plan. N: Nutrition: refer where necessary
What is a primary dressing?Come in contact with the wound. They can either: - Maintain adequate moisture - Absorb excess moisture - Add moisture
what are some general principals of wound care?The Patient! Pain, comfort and psychological considerations Manage exudate and fill cavities Dry wounds need moisture
what is the first line treatment for heart failure?Diuretics
What is the symptoms of SVT?Palpitations Pounding in the neck or head Chest discomfort (chest pain is unusual) Dyspnoea
what does a mental state exam involve?Behaviour and Appearance Affect and Mood (feelings) Thought process, content and perception (includes thoughts of harm to self or others) Orientation and cognition Motivation Insight and judgement
what are the factors that help with recovery of mental health? (CHIME)connectedness hope identity meaning empowerment
what are the barriers to gaining informed consent?Health literacy Communication problems Medical jargon Unfamiliar words English as an Additional Language (EAL) Hearing loss Time constraints Cognitive impairment
When assessing competence what should the doctor take into consideration?the seriousness of the patient’s medical condition the implications of treatment and non-treatment the patient’s current mental state and cognitive ability complexity of the information being given
when is WRITTEN consent required?the consumer is to participate in any research the procedure is experimental the consumer will be under general anesthetic there is significant risk of adverse effects to the consumer.
A child under the age of 16, is capable of providing consent to medical treatment “If the child has sufficient understanding and intelligence to enable him or her to understand fully what is proposed. True or false?True
the emphasis in mental health care has moved to a recovery and social wellbeing model of health, with more emphasis on human rights. True or false?True
The MHA promotes supported decision-making, aligns with the recovery and wellbeing model of mental health, and provides measures to minimise compulsory or coercive treatment, true or false?true
What are the key aims to define the circumstances in which compulsory assessment and treatment may occur?Ensure that individuals and the public are protected from harm Ensure that Patients Rights are protected Ensure that assessment and treatment occur in the least restrictive manner consistent with safety
Under the mental health act what is the definition of mental disorder to meet the criteria?*abnormal state of mind *abnormal state of mind must be of such a degree that it poses a serious danger to the health or safety of that person or others or it seriously diminishes the capacity of that person to take care of themselves.
under what sections of the mental health act can compulsory assessments begin for someone believed to be mentally disordered?section 8-15
under what section of the act can a judge make a compulsory treatment order?section 28-34
under what section a nurse has the power to detain a person for no more than 6 hours until a medical practitioner examines them if they believe a person may be mentally disordered?section 111
Process of compulsory assessment?Section 8 – application Section 8b – health practioner examines the patient (accompanies application form) Section 9 – DAO receives application and arranges psychiatrist assessment Section 10- preliminary assessment – psychiatrist record findings
What is the purpose if IV therapy?Restore and maintain fluid and electrolyte balance Administer IV medications Administer Blood and Blood Products Provide Parenteral nutrition
what are the most common veins a peripheral iv catheter is placed?cephalic vein Basilic vein Median cubital vein
what is the use of NON tunneled central venous catheters?pt’s requiring IV therapy for less than 5 days or up to a max of 10 days - short term use
what is the use of tunneled central venous catheters?for permanent IV access, for pt’s requiring IV therapy > 6 weeks with no max
why is a small canula best to deliver medication?Greater blood flow and haemodilation reducing damage from irritating solutions Reduced mechanical irritation and insertion trauma (not irritating sides of vessels)
What are the principals of Aseptic non-touch technique? (ANTT)Always cleanse hands effectively Non touch technique is used at all times (to protect key parts) Touch non-key parts with confidence Take appropriate infection prevention precautions
What are the factors that some medications put people at risk of iv fluids?*other medications in system *obesity *age *respiratory conditions
what are some things we need to be aware of before giving iv fluids/medications?*fluid restrictions *sodium restrictions *sugar(dextrose) restriction
what are the complications of peripheral IV therapy?Hematoma infection phlebitis infiltration EXTRAVASATION
What is iniltration and causes ?Partial or complete puncturing of the vessel due to: poor stabilisation of the limb. -poor location of the cannula - poor cannulation technique -fragility of patients veins
What causes infection at a IV site?Self seeding from a distant infection Introduction of skin organisms Poor aseptic technique Contaminated infusate/equipment General poor health of patient
What can cause phlebitis at IV site?Mechanical such as poor cannulation technique Chemical such as drug not diluted correctly
What is a hematoma and what causes it?The localised collection of blood in a tissue due to a break in the wall of a blood vessel Patient susceptibility Poor cannulation technique Trauma to IV site post insertion
what are considered high risk medications?opioids insulin anticoagulant potassium
What antibiotics are within the beta lactam class?penicillin's cephalosporins carbapenams monobactums
what is the mode of action of beta lactam antibiotics?They are bactericidal (kill bacteria) kills gram + and - and broad spectrum. Contains beta lactam ring which inhibits the synthesis of the peptidoglycan layer on the cell wall
What drugs are under the antibiotic class glycopeptides?vancomycin
What is the mode of action for vancomycin?only effective against gram-positive bacteria - bactericidal. inhibits the synthesis of the peptidoglycan layer on the cell wall
Nursing considerations for beta lactam antibiotics?Not be given to patients with a history of hypersensitivity to beta-lactam antibiotics >risk anaphylaxis May reduce the efficacy of oral contraceptives avoid alcohol need to adhere to full course
side effects of penicillin group?black hairy tounge hypersensitivity reaction GI upset Renal, hepatic dysfunction Rash, urticaria oral candidiasis
what is the mode of action of tetracyclines?inhibits bacterial protein synthesis - bacteriostatic
what is the mode of action of glycopeptides and what is an example?vancomycin. inhibits cell wall synthesis causing cell lysis - bactericidal
what is the mode of action of aminoglycosides and what is an example?gentamycin. inhibits bacterial protein synthesis - bactericidal
what is the mode of action of fluoroquinolones and what is an example?norfloxacin. inhibits DNA synthesis - bactericidal
what is the mode of action of tetracyclines and what is an example?doxycycline. inhibits bacterial protein synthesis - bacteriostatic
what is antibiotic resistance?when bacteria mutates or changes their structure and has the ability to resist certain antibiotics
what is the definition of pain?An unpleasant sensory and/or emotional experience
Things that can happen to the body as a result of unmanaged pain?• Mental distress • Burden to the family • Affect adls • Cardiovascular problems – tachycardia, hypertension, adrenaline
What are the two components of pain?The physical and psychological response
what is acute pain?normally a protective mechanism - usually come on suddenly - response to internal and external stimuli
what is chronic pain?Usually last longer than 6 months - increasing numbers of pain impulses
what is somatic pain?nociceptors of the skin, muscles and soft tissue are activated - well localized
what is visceral pain?nociceptors of the organs are activated - poorly localized
what is neuropathic pain?injury or disease to the nerves themselves
what are some types of neuropathic pain?diabetic neuropathy carpel tunnel phantom pain
what are the three systems involved with the perception of pain?Limbic system - emotion response to pain Reticular system - autonomic motor response - move hand away suddenly somatosensory - interpretation of pain
what are the inhibitory neurotransmitters involved with the modulation of pain?enkephalins (bodys natural opioids) endorphins serotonin
When completing a pain assessment, what should you ask?P – Provocation/palliation – what makes it better or worse Q – Quality/Quantity – burning, shooting, sharp, dull, nagging R – Region/radiation – S – severity T – timing – U – affecting you
What is the goals of pain management?Must use a holistic approach to pain management Every patient deserves adequate pain relief comfort function goals Important to use medication and non medication methods Always evaluate effectiveness
if a pain assessment is required in someone who is unable to self report pain (sedated, dementia) what should the nurse do?Attempts to obtain self report Search for potential causes of pain Observe patient behaviors ask family members
How should a nurse complete a pain assessment on a young child?Self report - what the child says ( the gold standard) Behavioural –how the child behaves  Physiological –clinical observations use FLACC assessment if child unable to communicate
what is increased intracranial pressure?increase of pressure inside the skull caused by the CFS, tissue or blood that can result in brain injury
what causes increased intracranial pressure?infections - meningitis brain injuries brain tumor aneurysm
symptoms of increased intracranial pressure?• Headache • Blurred vision • confusion • Vomiting
What causes abscesses and empyema's in the brain?Infection from an area of the body - The infection will cause your brain to swell from the collection of pus and dead cells that forms that cause ICP
treatment for abscesses and empyema's?Antibiotic therapy Surgery to drain the infected site-this allows immediate relief of pressure on the brain or spinal cord Sample is taken for bacterial identification-drug therapy can be altered to a more specific antibiotic surgery is too dangerous
what is multiple sclerosis?a disease of the central nervous system that affects movement, sensation and body functions - body attacks myelin on neurons
symptoms of MS?fatigue numbness lack of coordination weakness
what is the diagnostics for MS?MRI - number of lesions found
what medications can help manage MS?Disease modifying medications: Immunomodulators interferon beta 1- Decreases inflammation and prevent nerve damage that may cause symptoms of MS steroids for acute flare ups
what is gillian barr syndrome ?autoimmune disease - acute inflammatory demyelinating polyneuropathy of the peripheral nervous system characterized by neuropathy and weakness starting at the feet moving towards the head. monitoring of respiratory and cardiovascular status due to paralysis
what is epilepsy?Neurological disorder in which nerve cell activity in the brain is disturbed, causing seizures. occurs basically due to excessive abnormal firing of the neurons and fast spread of these impulses over the brain - thought to be an imbalance of GABA and glutamate
what is a seizure?burst of electrical activity between excitatory and inhibitory neurotransmitters causing temporary abnormalities in muscle tone or movements (stiffness, twitching or limpness), behaviors, sensations or states of awareness
what is the mode of action for sodium valporate(anticonsulvant/anti-epileptic)?blockade of voltage-dependent sodium channels and enhancing brain concentrations of GABA, an inhibitory neurotransmitter. This suppresses repetitive neuronal discharges that generate seizures in epilepsy
how is epilepsy diagnosed?Electroencephalogram (EEG) - check electrical activity in brain seizure diary
what are general seizures?involving the whole brain - tonic clonic, absence, atonic
nursing considerations for seizures?Stay calm – talk to person reassure Make the person safe Cushion the head Time the seizure Do not hold down Do not put anything in the mouth When the seizure ends place the person in the recovery position Stay with the person until they have fully recovered
what is Alzheimer's disease?progressive neurodegenerative disorder -amyloid plaques clump together outside the neuron leading to loss of synapses and neurofibrillary tangles occur in the neuron leading to death of the neuron, which results in neuron death and atrophy of the affected areas of the brain - loss of acetycholine (processing memory and learning)
Symptoms of Alzheimer's?Memory loss Confusion about the location of familiar places Taking longer to accomplish normal, daily tasks Trouble handling money and paying bills Compromised judgment, often leading to bad decisions
what medications can help alzheimers?there is no cure. cholinesterase inhibitors because acetylcholine is decreased in alzheimers
What is the mode of action of donzepil (cholinesterase inhibitor?block the action of the enzyme cholinesterase, which is responsible for breaking down acetylcholine. This increases levels of acetylcholine in the synaptic cleft
nursing considerations for neurodegenerative conditions?Catheterisation Bowel management Pain Management
what are the subtypes of dementia?alzheimers lewy body disease frontotemporal dementia vascular dementia
hippocampus and memory formation are affected very early on in alzheimers. true or false?true
what is tempofrontal dementia?Two key proteins are TDP-43 and tau, which abnormally accumulate in neural cells causing neurons to die and the brain to shrink- Stops the myelin forming stopping the action potentials firing
what is lewy body dementia?Protein deposits, called Lewy bodies, develop in nerve cells in the brain regions involved in thinking, memory and movement (motor control). cause death of neurons and shrinkage of brain. hallucinations, sleep disturbance and fluctuating cognitive changes, as well as physical or motor features of Parkinson's disease (e.g. tremors).
what is vascular dementia?Vascular dementia is associated with accumulated damage to blood vessels in the brain - starved of oxygen
risk factors for developing dementia?genetics old age diabetes obesity
what do nurses need to think about when someone has early stages of dementia?(1) keeping the mind active; (2) keeping the body active; (benefit from physical activity) (3) accessing appropriate support; ( (4) managing health conditions and nutrition. (diaetes etc
Non pharmalogical interventions for dementia?Music Therapy Reminiscence Therapy Aroma Therapy Massage
what is the pathophysiology of delirium?reduced production of acetylcholine or decreased acetylcholine transmission and inflammatory cytokines can cross the blood-brain barrier and affect brain function and neurotransmission
assessment tool for delirium?confusion assessment method(CAM) assess when patient is first admissioned and assess regualry after
what is delirium ?an acute disturbance in cognitive abilities resulting in confusion and functional decline that flucuates - can be hyperactive or hypoactive
how does the vomiting reflex happen?The oesophagus relaxes The diaphragm and abdominal muscles contract - increasing intra-abdominal pressure Epiglottis closes to stop regurgitated food travelling to the lungs Autonomic nervous system changes -Tachycardia, Increased salivation and peristalsis Expulsion of food
where is the vomitting centre located in the brain?medulla and contains muscarinic receptors
what things can break down the blood brain barrier?hypertension chemicals radiation trauma
what is the function of the chemoreceptor trigger zone?CVO organ - contains serotonin & dopamine receptors - stimulated by chemicals and cytoxic agents which then stimulates muscarinic receptors in the vomitting centre to induce vomitting reflex