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Index
»
CC LEC
»
Chapter 1
»
Endocrinology
level: Endocrinology
Questions and Answers List
level questions: Endocrinology
Question
Answer
• Processed under immunosero because it uses
Serum
the study of the endocrine system, hormones and role in the body. It influences the way we feel, we act, the things we do
Endocrinology
are essential in maintaining homeostasis and are sensitive to changes in the body
Hormones
• Network of ductless glands (No duct- vessel in which chemicals can stay before release)
Endocrine gland
endocrine cell found in glands will release a hormone directly to the blood stream and to the target cell
Secreting cells
• chemical products are passed out of the cell away from the gland in the means of vessel
Exocrine gland
• Chemical messengers (because they stimulate a certain process) that travel into the bloodstream to TARGET CELLS WITH specific receptors to the hormones and react in the presence of those substances.
Hormones
• Stimulated by an Imbalance in the body
Hormones
• Binds to specific receptors on the cell of origin resulting in self-regulation of its function
1. Autocrine
Side” binds to receptors in Adjacent cells
2. Paracrine
• Acts on immediately adjacent cell by direct cell-to-cell contact from one receptor to another
3. Juxtacrine
• It is similar to autocrine because it acts on itself but the manner is different because intracrine the hormone remains itself inside the cell
4. Intracrine
Pheromones- substances release from animals that causes a response in another organism
5. Ectrocrine (extra)
Generally, secretes releasing hormones: it will stimulate the other hormones, Have an effect in the organ
• Hypothalamus
Hypothalamus releases
thyroid releasing hormones
Releases secreting hormones; thyroid stimulating hormones
Pituitary
secrete hormones stimulated by the hormones in the hypothalamus. Ex. TSH- stimulated by the production of TRH from the hypothalamus.
ANTERIOR PITUITARY
not a true endocrine gland, not able to produce hormones. It will just store hormones from the hypothalamus Ex. ADH
POSTERIOR PITUITARY
• Goiter, enlarged neck, butterfly shaped organ found below the neck
Thyroid
Thyroid gland releases
T3, T4, Calcitonin
smallest endocrine gland which is embedded in thyroid gland (P shape), “marbles” releases PTH for calcium regulations.
• PARATHYROID
• Sitting on top of the kidneys “above kidneys”
3. Adrenals or Suprarenal
Adrenal Cortex
Aldosterone, Cortisol, Sex hormones
influences sodium levels
Aldosterone
hyperglycemic agent, increases glucose level for you to produce ore energy “stress hormone”
Cortisol
(All of us have testosterone (testes) and estrogen (ovary) it’s just that one predominates the other, the difference is the amount)
Sex hormones
Adrenal Medulla
Epinephrine, Norepinephrine, Adrenaline
– involved in fight or flight response
Epinephrine / Adrenaline, Noradrenaline Dopamine
• principle hyperglycemic agent: glucagon released by alpha cells of islets and Langerhans
Pancreas
Insulin: beta (decrease glucose) • Somatostatin – regulates insulin and glucagon released by delta cells
True
(vertebrates) one of usually two organs that produce ova and secrete estrogen and progesterone
Ovary
• Testosterone
6. Prostate / Testes
• EPO erythropoietin which is a hormone that increased the production of RBC
7. Kidneys
• Produces thymosin which increases T cell production (becomes smaller overtime, shrink)
Thymus
• located in the brain, responsible for melatonin which is a hormone responsible for sleep cycles
Pineal Gland
• Melanin (less melanin – lighter skin)
Skin
• Basically, proteins that has the same properties as proteins • A group of peptides will make up protein.
Peptides
Water soluble Lipid insoluble No transport protein Secondary messaging The receptor is outside
Peptides
Insulin FISH Vasopressin Glucagon LH Thyrotropin Somatotropin ACTH Oxytocin
Peptides
• Basically, made up of lipids • Derived from cholesterol • Properties are related to lipids
Steroids
Water insoluble Lipid soluble With transport protein Primary messaging The receptor is inside
Steroids
➢ Aldosterone ➢ Cortisol ➢ Estrogen ➢ Testosterone ➢ Progesterone
Steroids
depends on the type of hormone’s
Amines
T3, t4, Catecholamines
Amines
• basically, how hormones regulate themselves
Feedback mechanism
Increase in product = decrease activity
Negative feedback
increase in product = elevate activity
POSITIVE FEEDBACK
Homeostatic- purpose Inhibitor
Negative feedback
Non-homeostatic – does not maintain the balance Enhancers
Positive feedback
Luteinizing hormone
Negative feedback
• Defect in the target organ itself
Primary
• Defect in the pituitary gland or the organ that stimulate the target gland
2. SECONDARY
• Defect in the hypothalamus (secretes releasing hormones)
Tertiary