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Index
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PHARM MED ORG
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Chapter 2
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Reduction and Hydrolysis (Definitions)
level: Reduction and Hydrolysis (Definitions)
Questions and Answers List
level questions: Reduction and Hydrolysis (Definitions)
Question
Answer
1 Reduction of Aldehydes results to __ 2 Reduction of Ketones results to __
1 Primary Alcohol 2 Secondary Alcohol (The breakdown of C=O into C-OH)
1 Reduction of Nitro compounds results to __ 2 Reduction of Azo compounds results to __
1 Nitroso -> Hydroxylamine -> Primary amine 2 Azo -> Hydrazo -> Two Primary amines
1 Reduction of Sulfamidochrysoidine (Prontosil) will result to __ 2 Reduction of Sulfasalazine will result to __
1 Sulfanilamide and 1,2,4-Triaminobenzene 2 Sulfapyridine and 5-Aminosalicylic acid
Sulfoxide reduction, you cannot reduce a __
Sulfone
Reduction of Sulindac will result to __
Sulindac sulfide metabolite
1 Metabolism of ester, amides and lactams 2 Enzymes involved in this reaction are:
1 Hydrolytic Reactions 2 Non specific esterase (found in liver, kidney, intestine) Pseudocholinesterase (found in plasma) Amide (amidase, esterases and deacylases)
1 Hydrolysis of acetylsalicylic acid will result to __ 2 Hydrolysis of Methylphenidate will result to __ 3 Hydrolysis of Diphenoxylate will result to __
1 Salicylic acid and acetic acid 2 Ritalinic acid 3 Diphenoxylic acid (Difenoxin)