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level: DYES (SLIDE 80)

Questions and Answers List

level questions: DYES (SLIDE 80)

QuestionAnswer
Methyl p- Hydroxybenzoate White crystalline powder Soluble in water and alcohol Slightly soluble in nonpolar organic solvents Used as safeguard against mold growthMETHYLPARABEN
Methyl p- Hydroxybenzoate White crystalline powder Soluble in water and alcohol Slightly soluble in nonpolar organic solvents Used as safeguard against mold growthMETHYLPARABEN
Methyl p- Hydroxybenzoate White crystalline powder Soluble in water and alcohol Slightly soluble in nonpolar organic solvents Used as safeguard against mold growthMETHYLPARABEN
Hexamethyl-p-rosaniline chloride, crystal violet, methyl violet, methylrosaniline chloride Green powder or green flakes with a metallic sheen Soluble in water (1:35), alcohol (1:10) Insoluble in nonpolar organic solventsGENTIAN VIOLET
GENTIAN VIOLET 1 treatment of yeast infections 2 treatment of ringworm and yeast infections 3 Gential Violet Oral use is anthelmintic for __1) Vaginal Suppositories 2) 1%-3% solutions 3) strongyloidiasis (threadworm) and oxyuriasis
Mixture of chlorides of rosaniline and p- rosaniline Green crystalline powder with metallic appearance Soluble in water, alcohol Insoluble in etherBASIC FUCHSIN
topically for tx of fungal infections (ringworm and athlete’s foot)Carbol-fuchsin sol ( Castellani’s paint):
3,7-bis(dimethylamino)-phenazat hionium chloride (Urised) Dark green crystalline powder Tx for cystitis and urethrisis Bacteriostatic Colors the urine and stool blue greenMETHYLENE BLUE
1 Elemental mercury in ointments for localized infections and syphilis 2 impetigo, psoriasis, ringworm 3 treatment inflammation of eye but irrigating, cause hypersensitivity1 MERCURY COMPOUNDS (MERCURIALS) 2 Ammoniated mercury [Hg(NH2)Cl] 3 Mercuric ion
1 ORGANOMERCURIALS2 classes 2 Organic moiety increase __ solubility facilitating penetration into microorganisms and host tissues1 a) Compounds with at least one carbon-mercury bond that does not ionize readily b) Compounds with mercury bonded to heteroatoms (O, N, S) that ionize partially or completely- 2 lipid
3-(Hydroxymercuri)-4-nitro-o- resol inner salt BN: Metaphen Yellow powder Practically insoluble in water Sparingly soluble in alcohol and most organic solvents Nonirritating to mucous membrane, nonstaining Antiseptic for skin and ocular infectionsNITROMEROSOL
[(o-Carboxyphenyl)-thio]ethylmercury sodium salt BN: Merthiolate Cream-colored, water-soluble powder nonstaining and nonirritating Weakly bacteriostatic antiseptic applied topically in ointments or aq solutionsTHIMEROSAL
IDEAL PRESERVATIVES1 Effective at low concentration against all possible microorganisms 2Nontoxic and compatible with other constituents 3 Stable for the shelf life of the preparation
Esters of p-hydroxybenzoic acid (parabens): antifungal properties Toxicity is low, undergo rapid hydrolysis> quickly conjugated and excreted Metyl esters: molds Propyl esters: yeasts more lipid soluble is preferred for drugs in oil or lipophilic basesP-HYDROXYBENZOIC ACID DERIVATIVES
Methyl p- Hydroxybenzoate White crystalline powder Soluble in water and alcohol Slightly soluble in nonpolar organic solvents Used as safeguard against mold growthMETHYLPARABEN
Propyl p-hydroxybenzoate White crystalline powder Slighlty sol in water Soluble in most organic solvents Preservative against yeast growth Propylparaben Na: water soluble sodium salth of 4-phenol group, pH 10PROPYLPARABEN
N-Butyl p-hydroxybenzoate White crystalline powder Sparingly soluble in water Very soluble in alcohols and nonpolar organic solventsBUTYLPARABEN
Ethyl p-hydroxybenzoate white crystalline powder that is slightly soluble in water Soluble in alcohol and organic solventsETHYLPARABEN