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PHARM MED ORG
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ANTIHELMINTHS
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Level 1
level: Level 1
Questions and Answers List
level questions: Level 1
Question
Answer
1 Multicellular parasites 2 In beef 3 In Pork 4 Fish
1 Helminths 2 Taenia saginata 3 Taenia solium 4 Diphylobotrium latum
Helminths are divided into
1 Roundworms (Nemathelminths) -Class Nematoda 2 Flatworms (Platyhelminths) -Class Trematoda -Class Cestoda
Used in the treatment for Pinworm, Roundworm infestations
Piperazine
Drug Of Choice against Filariasis, Bancrofti, Onchocerciasis, Laviasis, Ascariasis Few adverse effect associated
Diethylcarbamazine Citrate (DEC)
Treatment for Pinworms and Roundworms causes spastic paralysis in susceptible helminths
Pyrantel Pamoate
Pyrantel Pamoate Side Effects:
GI Distress
Used to treat strongyloidiasis, enterobiasis, ascariasis, uncirasis, trichuriasis. Broad-spectrum Veterinary: control intestinal helminths in livestock
Thiabendazole
Thiabendazole is also used to control intestinal helminths in __
Livestock
Broad-spectrum ( whipworm, pinworm, roundworm, hookworm) Irreversibly blocks glucose uptake in susceptible helminths
Mebendazole (Vermox)
Single-dose treatment for ascariasis, New and Old world hookworm, trichuriasis Treatment in intestinal nematode infection ---- Absorption is enhance by fatty meal Undergo rapid first-pass metabolism to sulfoxide
Albendazole
Albendazole Side Effects
bone depression, elevation of hepatic enzymes, alopecia
Potent taeniacide that causes rapid disintegration of worm segments and scolex Mandatory in the treatment of pork tapeworm infestation
Niclosamide
Niclosamide how to use
A saline purge 1 to 2 hours after ingestion of the taeniacide is recommended to remove the damaged scoles and worm segments.