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level: level 2

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level questions: level 2

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is prepared by mixing equal volumes of Alcohol, USP, and Purified Water, USP. Strength is not exactly half that of the more concentrated alcohol but slightly greater, approximately 49%. Useful hydro alcoholic solvent in various pharmaceutical processesDiluted Alcohol, NF
contains about 70% ethyl alcohol by volume, the remainder consisting of water, denaturants with or without color additives and perfume oils, and stabilizers. It is employed as a RUBEFACIENT externally and as a soothing rub for bedridden patients, a germicide for instruments, and a skin cleanser prior to injection. It also used as a vehicle for topical preparations. The product is volatile and flammable and should be stored in tight containers remote from fire.Rubbing Alcohol Synonym: Alcohol Rubbing Compound
In Rubbing alcohol, 1) Each 100mL must contain __ 2 Denaturants employed should be __1) not less than 355 mg Sucrose octaacetate or 1.4 mg denatonium benzoate 2) 8 parts acetone 1.5 parts methyl isobutyl ketone 100 parts ethyl alcohol
a clear syrupy liquid with a sweet taste. It is miscible with both water and alcohol. It is used in many internal preparations. has preservative qualities and is often used as a stabilizer and as an auxiliary solvent in conjunction with water or alcohol.Glycerin, USP (Glycerol)
1) about 70% by volume isopropyl alcohol, the remainder consisting of water with or without color additives, stabilizers, and perfume oils. It is used externally as a rubefacient and soothing rub and as a vehicle for topical products. 2) Commercially, This percent of the solution is for diabetic patients, disinfecting needles, syringes and skin1 Isopropyl Rubbing Alcohol 2) 91% isopropyl alcohol solution
a viscous liquid, is miscible with water and alcohol. It is a useful solvent with a wide range of applications and is frequently substituted for glycerin in modern pharmaceutical formulations.Propylene Glycol, USP
obtained by distillation, ion exchange treatment, reverse osmosis, or other suitable process. intended for use in the preparation of aqueous dosage forms, except those intended for parenteral administration (injections).Purified Water, USP
Purified Water, USP compared with ordinary drinking watermore free of solid impurities. When evaporated to dryness, it must not yield greater than 0.001% of residue (1 mg of total solids per 100 mL of sample evaporated). Clear, colorless, odorless and neutral or only slightly acidic or alkaline intended for use in the preparation of aqueous dosage forms
Distillation method to prepare purified water1 The first portion of aqueous distillate (about the first 10% to 20%) must be discarded 2 The last portion of water (About 10% of the original volume of water) remaining in the distillation apparatus must be discarded and not subjected to further distillation Summary: First 10% and Last 10% must be discarded
On a large or small scale, offers a number of advantages over the distillation method. Heat is eliminated Permits ease of operation, minimal maintenance, and a more mobile facilityIon-exchange method
There are mainly two types of resins in column ion-exchange1 the cation, or acid exchangers 2 the anion, or base exchange resins
1 permit the exchange of the cations in solution (tap water) with hydrogen ion from the resin 2 permit the removal of anions.1 the cation, or acid exchangers 2 the anion, or base exchange resins
Water purified in this manner (Ion-exchange method) is referred to as __demineralized or de - ionized water.
1 In this process, a pressurized stream of water is passed parallel to the inner side of a filter membrane core. A portion of the feed water permeates the membrane as filtrate. 2 The water that has passed through the system is referred to as the __ 3 The flow in this crossflow system is from a __ concentrated to __ concentrated solution thus the term reverse osmosis1 Cross-flow (tangential flow) membrane filtration 2 concentrate (contaminants). 3 more, less
Reverse osmosis removes virtually allVirus Bacteria Pyrogens Organic molecules 90%-99% of all ions.