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level: level 5 - Elixirs

Questions and Answers List

level questions: level 5 - Elixirs

Question	Answer
clear, sweetened hydroalcoholic solutions intended for oral use and are usually flavored to enhance their palatability.	Elixirs
1 these elixirs are employed as vehicles 2 are used for the therapeutic effect of the medicinal substances they contain.	1 Nonmedicated elixirs 2 medicated elixirs
Elixirs compared with syrup 1 Compared with syrups, elixirs are usually __	1 less sweet and less viscous 2 better able than aqueous syrups to maintain both water- soluble and alcohol-soluble components in solution 3 requires a specific blend of alcohol and water to maintain all of the components in solution.
__ are frequently employed in elixirs as ADJUNCTIVE SOLVENTS	1 glycerin 2 propylene glycol In addition to alcohol and water
1 Although many elixirs are sweetened with sucrose or with a sucrose syrup, some use __ 2 All elixirs contain __ to increase their palatability, and most elixirs have __ to enhance their appearance.	1 Sorbitol, Glycerin, and/or Artificial Sweeteners. 2 Flavorings, Coloring Agents
Elixirs containing __ are usually SELF-PRESERVING and do not require the addition of an antimicrobial agent	more than 10 to 12% alcohol
1 One advantage of elixirs over their counterpart drugs in solid dosage forms is __ 2 disadvantage of elixirs for children and for adults	1 flexibility and ease of dosage administration to patients 2 the alcoholic content
Elixirs storage	tight, light-resistant containers and protected from excessive heat.
Preparation of Elixirs	1 SIMPLE SOLUTION WITH AGITATION or by admixture of two or more liquid ingredients. Alcohol-soluble and water-soluble components are generally dissolved separately in alcohol and in purified water, respectively.
1 The final mixture in preparing the elixir will be __ in appearance because of separation of some of the flavoring oils by the reduced alcoholic concentration. 2 The Filter to the preparation of Elixirs	1 Cloudy 2 Talc
The presence of __ in elixirs generally contributes to the 1 Solvent effect of the hydroalcoholic vehicle, 2 Assists in the dissolution of the solute, and 3 Enhances the stability of the preparation. but they also, 1 adds viscosity> slow rate of filtration	1 Glycerin 2 Syrup 3 Sorbitol 4 PEG GSSP
__ may be useful to the pharmacist in the extemporaneous filling of prescriptions involving 1 The addition of a therapeutic agent to a pleasant-tasting vehicle, 2 Dilution of an existing medicated elixir.	Nonmedicated Elixirs
1 In selecting a liquid vehicle for a drug substance, the pharmacist should be concerned with the solubility and stability of the drug substance in water and alcohol. TRUE OR FALSE? 2 If this vehicle is selected, the alcohol should be slightly above the amount needed to effect and maintain drug's solution	1 TRUE 2 Hydroalcoholic vehicle
The three most commonly used NONMEDICATED ELIXIRS were	1 Aromatic elixir 2 Compound benzaldehyde elixir 3 Isoalcoholic elixir ACI (ELIXIR ASAY)
contain single therapeutic agent , dosage of the drug is ↑ or ↓ simple taking more or less of the elixir	Medicated Elixirs
Examples of Medicated Elixirs	1 Antihistamines elixirs 2 Barbiturate sedative/hypnotic elixirs 3 Phenobarbital Elixir 4 Digoxin Elixir (ELIXIR DAP / DAB / DAH)