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Index
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DDS LEC FINALS
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Chapter-13.-Solutions.pptx
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level 9
level: level 9
Questions and Answers List
level questions: level 9
Question
Answer
1 Most of the ADRENERGIC drugs used in nasal decongestant solutions are synthetic compounds similar to __ 2 Most solutions for nasal use are packaged in dropper bottles or in plastic spray bottles, usually containing __ of medication.
1 Epinephrine 2) 15 to 30 ml
The vast majority of preparations intended for intranasal use contain __ (AGENTS) and are employed for their decongestant activity on the nasal mucosa.
adrenergic agents
Nasal preparations: __
1 Nose drops 2 Sprays 3 Jellies
Most nasal decongestant solutions are: (characteristics)
1 Aqueous preparations 2 Rendered isotonic to nasal fluids (approximately Equivalent to 0.9% sodium chloride), 3 Buffered to maintain drug stability (pH5.5-6.5) 4 Stabilized and preserved as required
1 Most of the adrenergic drugs used in nasal decongestant solutions are synthetic compounds similar to __ 2 Most solutions for nasal use are packaged in dropper bottles or in plastic spray bottles, usually containing __ of medication. 3 The concentration of adrenergic agent is ranging from about __
1 Epinephrine 2) 15 to 30 ml 3) 0.05 to 1.0%.
Nasal decongestant solutions are employed in the treatment of 1 __ of the common cold and for vasomotor and allergic rhinitis including 2 __
1 rhinitis 2 hay fever, sinusitis.
The frequent use or their use for prolonged periods may lead to __ of the nasal mucosa.
Chronic Edema they should be used no longer than 3 to 5 days
__ are usually placed in the ear canal by drops or in small amounts for the removal of excessive cerumen (ear wax) or for the treatment of ear infections, inflammation, or pain.
Ear preparations (Otic preparations) ex. Cerumen-removing solutions
Commonly used agents to soften impacted cerumen for its removal Cerumen-removing solutions
1 Light mineral oil 2 Vegetable oils 3 Hydrogen peroxide Recently developed: 1 Solution of Synthetic surfactants
Eardrops commercial products
1 Triethanolamine polypeptide oleate-condensate in propylene glycol 2 Carbamide peroxide in glycerin/ Propylene glycol
Drugs used topically in the ear for their antiinfective activity include: chloramphenicol colistin sulfate neomycin polymyxin B sulfate nystatin
Anti-infective, anti-inflammatory, and analgesic ear preparations
Anti-inflammatory agents (ear preparations)
1 Hydrocortisone 2 Dexamethasone sodium phosphate 3 Acetic acid (2%) in aluminum acetate solution 4 Boric acid (2.75%) in isopropyl alcohol
Topical analgesics (for the ear)
1 Antipyrine 2 Local anesthetic Benzocaine in a vehicle of propylene glycol or anhydrous glycerin
Used in preserving Otic preparations (Preservatives)
1 Chlorobutanol (0.5%) 2 Thimerosal (0.01%) 3 Combinations of the parabens
Otic preparation stabilizers
Sodium bisulfite (antioxidant)