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level: Macrolide Uses and Side Effects

Questions and Answers List

level questions: Macrolide Uses and Side Effects

QuestionAnswer
High doses of macrolides causes __Reversible auditory impairment
Macrolides stimulates __ which causes gastric contractions, hasten gastric emptying & promote intestinal motilityMotilin receptors
Hepatitis cholestatic jaundice occur with this after 2 weeksEstolate & Ethyl Succinate
This form causes Hypersensitivity reactionsEstolate form
Macrolide Side Effects1 Diarrhea 2 Ototoxicity 3 Hepatic toxicity 4 Jaundice 5 Inhibit P450 6 Skin rash Mnemonic: DO Heal JIsuS (DOH JIS)
Macrolide Uses1 Upper Respiratory Tract (Pharyngitis, Tonsillitis, Sore throat) 2 Otitis Media 3 Lower Respiratory Tract (Pneumonia, Legionnaires, Anthrax, MAC) 4 Ulcers (H.pylori) 5 Uncomplicated Skin Infections 6 STDs (Chlamydia, Gonorrhea, Chancroid disease)
Erythromycin Side Effects1 Cholestatic hepatitis (estolate) 2 Abdominal cramps, epigastric distress, diarrhea