level: Macrolide Uses and Side Effects
Questions and Answers List
level questions: Macrolide Uses and Side Effects
Question | Answer |
---|---|
High doses of macrolides causes __ | Reversible auditory impairment |
Macrolides stimulates __ which causes gastric contractions, hasten gastric emptying & promote intestinal motility | Motilin receptors |
Hepatitis cholestatic jaundice occur with this after 2 weeks | Estolate & Ethyl Succinate |
This form causes Hypersensitivity reactions | Estolate form |
Macrolide Side Effects | 1 Diarrhea 2 Ototoxicity 3 Hepatic toxicity 4 Jaundice 5 Inhibit P450 6 Skin rash Mnemonic: DO Heal JIsuS (DOH JIS) |
Macrolide Uses | 1 Upper Respiratory Tract (Pharyngitis, Tonsillitis, Sore throat) 2 Otitis Media 3 Lower Respiratory Tract (Pneumonia, Legionnaires, Anthrax, MAC) 4 Ulcers (H.pylori) 5 Uncomplicated Skin Infections 6 STDs (Chlamydia, Gonorrhea, Chancroid disease) |
Erythromycin Side Effects | 1 Cholestatic hepatitis (estolate) 2 Abdominal cramps, epigastric distress, diarrhea |