level: level 1
Questions and Answers List
level questions: level 1
| Question | Answer |
|---|---|
| Lincosamides naming end in __ | mycin / in ex. Clindamycin, Lincomycin |
| Lincomycin Characteristics | 1 Sulfur-containing antibiotics 2 Isolated from Streptomyces lincolnensis 3 Resemble macrolides in antibacterial spectrum and Mode of action |
| Sulfur-containing antibiotics isolated from Streptomyces lincolnensis Most active and medically useful of compounds obtained from fermentation Resemble macrolides in antibacterial spectrum and MOA Clindamycin: 7-chloro-7 deoxy Active against GRAM POSITIVE COCCI, non-spore forming anaerobic bacteria, actinomycetes, mycoplasma, Plasmodium Inhibit 50s ribosomal subunit May be bacteriostatic/ bactericidal | Lincomycin |
| ADR to vancomycin IV that may occur with the FIRST DOSE of vancomycin or when the drug is administered TOO FAST Flushing of the face and neck, pruritis, hypotension PREVENTION: Slow rate of injection | RED MAN SYNDROME |
| Decreases the effect of RED MAN SYNDROME | Benadryl |