level: level 3 -SAR
Questions and Answers List
level questions: level 3 -SAR
| Question | Answer |
|---|---|
| Effects of ring A on activity of benzodiazepine which is the preferred ring type? | Aromatic ring |
| Electron withdrawing group at position __ increases activity of benzodiazepine | 7 (more electronegative) |
| Phenyl ring at position __ increases activity of benzodiazepine | 5 |
| Positions __ are not applicable for any constituent in benzodiazepine | 6, 8 & 9 |
| positions 2 and 6 substituted with __ increases activity for benzodiazepine | Electron withdrawing groups |
| substitution at __ greatly reduces activity of benzodiazepine | 4 |
| maximum number of carbon in Alcohol CNS Depressants | carbon 8; more than 8 is less activity |
| Is the most potent in alcohol CNS Depressants | Tertiary |
| __ of OH in alcohol CNS Depressants increase depressant potency | Carbamylation |