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level: DRUG OF CHOICE

Questions and Answers List

level questions: DRUG OF CHOICE

Question	Answer
• DOC for both PARTIAL SEIZURES AND GENERALIZED TONIC-CLONIC SEIZURES • DOC TRIGEMINAL NEURALGIA • MANIA (BIPOLAR DISORDER)	CARBAMAZEPINE
the oldest nonsedative antiseizure drug	PHENYTOIN • Dilantin®
• OLDEST ANTISEIZURE • derivative of BARBITURIC ACID • LONGEST ACTING BARBITURATES	PHENOBARBITAL • Luminal®
Partial seizures (THIRD LINE DRUG FOR REFRACTORY CASES)	FELBAMATE
• Originally Planned As SPASMOLYTIC • ADJUCT against PARTIAL SEIZURES AND GENERALIZED TONIC-CLONIC SEIZURES • POSTHERPETIC NEURALGIA	GABAPENTIN • Neurontin®
APPROVED for use in NEUROPATHIC PAIN, including PAINFUL DIABETIC PERIPHERAL NEUROPATHY and POSTHERPETIC NEURALGIA ADJUNCTIVE treatment of partial seizures	PREGABALIN
ADJUNCTIVE therapy in the treatment of PARTIAL-ONSET SEIZURES WITH OR WITHOUT SECONDARY GENERALIZATION in PATIENTS WITH EPILEPSY 16 YEARS and older	LACOSAMIDE • Vimpat®
ADJUNCTIVE treatment of PARTIAL SEIZURES IN ADULTS AND CHILDREN, for PRIMARY GENERALIZED TONIC-CLONIC seizures and for MYOCLONIC SEIZURES OF JUVENILE MYOCLONIC EPILEPSY	LEVETIRACETAM
derivative of nipecotic acid and was "RATIONALLY DESIGNED" as an inhibitor of GABA uptake	TIAGABINE Gabitril®
• Effective against PARTIAL AND GENERALIZED TONIC-CLONIC SEIZURES • WEST'S SYNDROME, LENNOX-GASTAUT SYNDROME, ABSENCE SEIZURES -->>• MIGRAINE <<--	TOPIRAMATE • Topamax®
drowsiness occurs early in the treatment and if the initial dose is TOO LARGE	PRIMIDONE
DOC for ABSENCE SEIZURE	ETHOSUXIMIDE • Zarontin®
Very effective against ABSENCE SEIZURE and is often PREFERRED when the patient has CONCOMITANT GENERALIZED TONIC-CLONIC ATTACKS	SODIUM VALPROATE • Depakene®
former DOC for ABSENCE SEIZURE	Trimethadione
MORE EFFECTIVE AND LONGER ACTING THAN DIAZEPAM for STATUS EPILEPTICUS	LORAZEPAM • Ativan®
APPROVED in USA as an adjunct treatment of COMPLEX PARTIAL SEIZURES IN ADULTS	CLORAZEPATE • Tranxene®