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Index
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DRUG DISCOVERY DEVELOPMENT (DDD)
 »Â
Chapter 1
 »Â
Models for Studying Diseases
level: Models for Studying Diseases
Questions and Answers List
level questions: Models for Studying Diseases
Question
Answer
By growing both diseased and healthy cells in cell cultures, researchers can study differences in cellular processes and protein expression.
Cell cultures
Genes and proteins found in humans may also be found in other species. The functions of many human genes have been revealed by studying parallel genes in other organisms.
Cross-species studies:
These are substances, often proteins, that can be used for measuring a biological function, identifying a disease process, or determining responses to a therapy. They also can be used for diagnosis, for prognosis, and for guiding treatment.
Biomarkers
the study of protein activity within a given cell, tissue or organism. Changes in protein activity can shed light on the disease process and the impact of medicines under study.
Proteomics