| How to get ionized/ non ionized forms of a product? | Using Henderson's |
| Talk about aspirin absorption | Most aspirin is non-ionized so it gets easier to blood
As a defense of excess aspirin, we administer bicarbonate to alkalinize stomach and not absorb aspirin by becoming ionized |
| What is carrier-mediated membrane transport? | For non-lipid soluble molecules, rapid, active transport (if against gradient) or facilitated (if with gradient)
Active (needs energy, has saturation, selectivity and competitiveness/ occurs at specific places like BBB neurons and renal tubules and liver)
Facilitated (No energy needed, just a carrier, usually for endogenous products but can be used by drugs (glucose by RBC/ Choline by neurons to make Ach) |
| How is filtration transport? | Through pores like urinary excretion |
| How are endo and exocytosis? | Endo (phago or pino) and Exo (NTs) |
