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Index
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MANUFACTURE FINALS
»
Chapter 1
»
Level 3
level: Level 3
Questions and Answers List
level questions: Level 3
Question
Answer
Prepared from FRESH RIPE FRUIT Aqueous; USED FOR MAKING SYRUPS; Employed as VEHICLES and FLAVORANTS for other drug product. Fresh ripe fruit are allowed to stand at room temperature for several days until the pectin (structural fibers that are naturally present in fresh ripe fruits) are destroyed by enzymatic action. As a result, it will yield a CLEAR SOLUTION WITH ALCOHOL.
Juices
Juices 1 Preservative such as __ is employed if fresh ripe fruit is used in the preparation. 2 Fresh ripe fruit are allowed to stand at room temperature for several days until the __ (structural fibers that are naturally present in fresh ripe fruits) are destroyed by enzymatic action. As a result, it will yield a __ 3 Pectin causes __ in the final syrup
. 1 benzoic acid 2 pectin, clear solution with alcohol 3 precipitation
Type of Juices
1 Commercial juices 2 Cranberry juice
1 used to prepare extemporaneous preparation of CHOLESTYRAMINE (substance used to lower high levels of cholesterol in blood). 2 Used in controlling some urinary tract infections and also UROLITHIASIS.
1 Orange, apple, grape, and mixed vegetables 2 Cranberry juice
These are designed to be ADMINISTERED IN NASAL PASSAGES. Either in DROPS OR SPRAYS also in the FORM OF EMULSIONS OR SUSPENSIONS. BIOAVAILABILITY of this are usually DECREASE as MOLECULAR WEIGHT OF THE COMPOUND INCREASES. To enhance, employ surfactant to enhance the absorption of larger molecules.
Nasal Solutions
We also have nasal solution in the form of emulsions or suspensions. Since they are intended for nasal, they should be maintained in isotonic and slightly buffered to maintain a pH of __
5.5 – 6.5 (pH)
EFFECTS of Nasal Solutions 1 they give Local sympathomimetic effects. These 2 drugs is used as a decongestant. 2 gives Systemic effects; (Used for the TREATMENT OF DIABETES INSIPIDUS) 3 gives Systemic effects; (Used for MILK PRODUCTION PRIOR TO BREAST FEEDING.)
. 1 Ephedrine sulfate nasal solution USP, and Naphazoline hydrochloride nasal solution USP. 2 Lypressin nasal solution USP 2 Oxytocin nasal solution USP
Also known as EAR OR AURAL PREPARATION Used for the REMOVAL OF EXCESSIVE CERUMEN OR EARWAX used for the TREATMENT OF EAR INFECTIONS, INFLAMMATIONS, OR PAIN MAIN SOLVENT includes WATER AND GLYCERIN OR PROPYLENE GLYCOL.
Otic Solutions
In Otic Solutions, __ permits the drug to REMAIN IN THE EAR for a long time. Anhydrous form of this reduces the swelling around the ear tissues by removing moisture.
glycerin
1 Used to relieve pain, congestion, and swelling cause my MIDDLE EAR INFECTION 2 used to TREAT INFECTIONS OF EAR CANAL. It also helps provide relief from redness, irritation, and discomfort of certain ear problems.
1 Antipyrene and benzocaine otic solution 2 Neomycin, polymyxin B sulfates, and hydrocortisones otic solutions
Must meet USP requirements on sterility, total solids, and bacterial endotoxin tests. Sterile non pyrogenic solutions ❖ Sterile NON PYROGENIC SOLUTIONS ❖ Purpose: to wash or bathe surgical incisions such as wounds or body tissues. ❖ USED DIRECTLY IN OPEN WOUNDS because they are prone to infections. ❖ Prepared by DISSOLVING ACTIVE INGREDIENTS IN WATER FOR INJECTION.
Irrigation solutions
TYPES OF Irrigation solutions
1 Acetic acid Irrigation or the bladder Irrigation 2 Dimethyl Sulfoxide Irrigation 3 Glycine Irrigation 4 Ringer’s Irrigation 5 Neomycin and Polymyxin B Sulfates Solution for Irrigation 6 Sodium Chloride Irrigation
1 directly USED TO CLEAN BLADDER 2 Used to relieve the INTESTINAL CYSTITIS or INFLAMMATION OF BLADDER
1 Acetic acid Irrigation or the bladder Irrigation 2 Dimethyl Sulfoxide Irrigation
1 Used for TRANSURETHRAL PROSTATIC RESECTION (a surgical procedure that involves cutting away a section of a prostate. Usually enlargement of prostate= cant urinate) 2 Commonly used for GENERAL IRRIGATION.
1 Glycine Irrigation 2 Ringer’s Irrigation
1 Used for infections. 2 Used for washing wounds.
1 Neomycin and Polymyxin B Sulfates Solution for Irrigation 2 Sodium Chloride Irrigation