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Index
»
PHARMACOLOGY 2
»
wk12-13 Antimicrobials,antifungals.pptx
»
Level 8 - VIDEO LEC 3
level: Level 8 - VIDEO LEC 3
Questions and Answers List
level questions: Level 8 - VIDEO LEC 3
Question
Answer
effective in the TREATMENT OF MRSA (Methicillin Resistant Staphylococcus aureus) good mainly at being able to TREAT GRAM-POSITIVE BACTERIA ○ MRSA ○ CLOSTRIDIUM DIFFICILE ○ RESISTANT COAGULASE NEGATIVE BACTERIA
Vancomycin
What does vancomycin do?
1 binds to CARBOXYL END. 2 hinders that peptide bond formation.
TREAT weird type of bacteria that's NOT FOR GRAM-POSITIVE and FOR GRAM-NEGATIVE BACTERIA TO TREAT TUBERCULOSIS by MYCOBACTERIUM
ISONIAZID
Mycobacterium don't have a cell wall that's made up of peptidoglycan, cell wall is made up of __
Mycolic acid
What does Isoniazid do?
1 inhibits the mycolic acid synthase
FOLIC ACID SYNTHESIS 1 Para-aminobenzoic acid + Pteridine = __ this reaction is catalyzed by __ 2 (1) is then converted into __ 3 (2) is then converted into __ this reaction is catalyzed by __ 4 (3) helps in the synthesis (final product) of __
. 1 Dihydropteroic acid, catalyzed by: dihydropteroate synthetase (DHPS) enzyme 2 Dihydrofolate or Dihydrofolic acid (DHF) 3 Tetrahydrofolate or Tetrahydrofolic acid catalyzed by: Dihydrofolate reductase 4 Purines & Pyrimidines
are important because they are COMPONENT IN MAKING UP THE DNA.
Purines & Pyrimidines
1 Dihydropteroate synthetase enzyme inhibitor DRUG 2 Dihydrofolate reductase enzyme inhibitor DRUG
1 Sulfamethoxazole (Sulfonamides) 2 Trimethoprim
INHIBITS DIHYDROPTEROATE SYNTHETASE. acts like a SUBSTRATE ANALOG used to treat TOXOPLASMOSIS use to treat NOCARDIOSIS used to URINARY TRACT INFECTIONS (UTI)
Sulfamethoxazole (Sulfonamides)
a PARASITIC INFECTION which is CAUSED BY the different types of CATS. the cats can actually pass on this parasite very DANGEROUS especially TO PREGNANT WOMEN
TOXOPLASMOSIS
bacteria they can cause infection, specifically within the PULMONARY, so WITHIN THE LUNGS are with EVEN ON THE SKIN too.
Nocardiosis
GOOD at being able to TREAT CERTAIN TYPES OF ENTEROBACTERIA GRAM (-)
Trimethoprim
gram-negative bacteria work within the ENTERIC NERVOUS SYSTEM causes damage, it can CAUSE a lot of certain types of GASTROINTESTINAL TRACT INFECTIONS.
Enterobacteria
Called bactrim (brand name) TREAT RESPIRATORY TRACT INFECTIONS TREAT condition PNEUMOCYSTIS CARINII
Trimethoprim + Sulfamethoxazole
CAUSED BY YEAST MORE COMMON in individuals who are IMMUNOCOMPROMISED LIKE HIV OR AIDS PATIENTS DANGEROUS TYPES OF INFECTIONS
Pneumocystis carinii