Screen > age 50 or if high risk 10 years earlier that affected family member . Screen with FOBT annually, flex sig Q 5 years, colonoscopy q 10 yr., FIT/DNA every 1-3 years. If > 2 polyp adenoma recheck in 3 years, If < 2 polyps repeat in 5 years. If hyper plastic repeat in 10 years. Stop screening after 85. Individualize b/w 76-85 High risk: Hx of polyp Low risk polyp: 1-2 small, < 1 cm, tubular adenoma: Screen colonoscopy Q 5 years High risk polyp: > 3 adenomas, > 1cm, villous: Screen colonoscopy every 3 years Personal hx of colon cancer : Screen at 1,3, and 5 years.