Question:
How are Nonhomologous End-Joining and how do they Repair Double-Strand Breaks?
Author: Noura Al shalanAnswer:
-Repair of double-strand breaks when homologous sequence is not available occurs through a nonhomologous end-joining (NHEJ) reaction. -The NHEJ pathway can ligate blunt ends of duplex DNA. -Mutations in double-strand break repair pathways cause human diseases.
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