Question:
How are nucleic acids polymerized?
Author: H KAnswer:
They occur as nucleoside monophosphates, however nucleotides that serve as building blocs are nucleoside triphosphates. Two adjacent nucleotides are always joined by phosphodiester bond between C'5 and C'3 of each nucleotide, nucleotides lose one or two phosphate groups to supply required energy for the ester bonds.
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