L-12 Modeling protein Structure: Explain the first generation method single residue statistics?

Question

Explain the first generation method  single residue statistics?

Shay 1vcc · Accepted Answer

Chou & Fasman (1974 & 1978) :
Some residues have particular secondary-structure preferences. Based on empirical frequencies of residues in -helices, -sheets, and coils.
Examples: Glu α-helix Val β-strand
Accuracy: Q3 = 50-60%

L-12 Modeling protein Structure

Explain the first generation method single residue statistics?

Chou & Fasman (1974 & 1978) : Some residues have particular secondary-structure preferences. Based on empirical frequencies of residues in -helices, -sheets, and coils. Examples: Glu α-helix Val β-strand Accuracy: Q3 = 50-60%

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