What are the two types of antigens that cause hypersensitivity?

1- responses to foreign antigens (microbes and noninfectious environmental antigens) may cause tissue injury, especially if the reactions are repetitive or poorly controlled. 2-the immune responses may be directed against self (autologous) antigens, as a result of the failure of self-tolerance.Responses against self antigens are termed autoimmunity, and disorders caused by such responses are called autoimmune diseases