Talk about SER function in detoxication of xenobiotics.

Happens in the liver, nut many organs also contribute to this process (skin, lungs, intestine). Detoxication is transformation of toxic hydrophobic parent chemicals into less toxic hydrophilic ones, which are then eliminated by kidney or liver and through urine or bile products respectively. It is carried out by a system of oxygen transferring enzymes called oxygenases having broad specificity for a wide variety of substrates, among them there is the family of cytochromes P450 present in SER.