Question:
Talk about Golgi role in glycosylation.
Author: H KAnswer:
Assembly of sugar motifs to protein is started in RER and continued in Golgi. Sugar motifs resulting from N-glycosylation in Golgi are matured by adding and removing monosaccharides catalyzed by different enzymes and different cisternae, Also Golgi plays a role in O-glycosylation, sugar motif is connected to polar OH side chain of aa (serine or threonine). Glycosylation is necessary for protein maturation and folding and targeting destinations. This is in addition to lipid glycosylation (BG)
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