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Cytology

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Question:

Talk about mitotic spindle

Author: H K



Answer:

Duplicated centrioles is initially happening. Disassembly of cytoskeleton components (MT AND IF) then pair of centrosomes increase formation of MT so that asters appear. centrosomes repel to opposite sides because of MT synthesis extending the spindle, some cells have no centrioles so minus ends of MT join by activity of motor proteins. Spindle is of three kinds: Astral MT (outward of centrosome, help positioning and division plane) Chromosomal or Kinetochore MT (Attach to chromosomes) Polar or interpolar MT (overlap with counterpart from opposite pole, responsible for cell stretching during cytokinesis.


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H K
H K