Acute leukemia presentations

Marrow failure Anaemia: fatigue, SOB, headaches, palpitations Leukopenia (low WBC count): infections, mouth ulcers Neutropenia is the biggest concern Thrombocytopenia: purpura, bleeding, bruising Hyperviscosity due to leucocytosis Headaches Breathlessness Visual blurring Confusion Leukaemic infiltration AML can cause gingival hypertrophy skin lesions ‘chloromas’ Hepatosplenomegaly