Question:
Describe sympathetic effects on cardiac electrophysiology
Author: Donata NshimyicizanyeAnswer:
Noradrenaline (NA) released at nerve endings. Binds to β1-adrenoreceptors. Increases Ca2+and If currents. Increasedslopeofphase4 in pacemaker cells. Increased SAN depolarization rate >>> Increased HR (Positive chronotropy)
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Author
Donata Nshimyicizanye