asthma drugs: good affinity for alpha and beta adrenoceptors. increasing the size of this substituent increases selectivity for beta receptors and then for beta 2 receptors.
replacing one of the catechol -OH groups by -CH2OH or changing its ring position reduces inactivation by neuronal and non-neuronal uptake.

Question

good affinity for alpha and beta adrenoceptors. increasing the size of this substituent increases selectivity for beta receptors and then for beta 2 receptors. 
replacing one of the catechol -OH groups by -CH2OH or changing its ring position reduces inactivation by neuronal and non-neuronal uptake.

georgia reeves · Accepted Answer

adrenaline as a natural ligand for beta adrenoceptors bronchodilators and how to make it more selective to beta 2

asthma drugs

Good affinity for alpha and beta adrenoceptors. increasing the size of this substituent increases selectivity for beta receptors and then for beta 2 receptors. replacing one of the catechol -OH groups by -CH2OH or changing its ring position reduces inactivation by neuronal and non-neuronal uptake.

Adrenaline as a natural ligand for beta adrenoceptors bronchodilators and how to make it more selective to beta 2

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