BBS2001 Threats and Defence Mechanisms: what do TLR4, TLR5, TLR9, NOD-1 and NOD-2 and NLRP3 recognise respectively?

Question

what do TLR4, TLR5, TLR9, NOD-1 and NOD-2 and NLRP3 recognise respectively?

Mirte Schattorie · Accepted Answer

TLR4 and NLRP3-> LPS
TLR5 -> bacterial flagella
TLR9 -> bacterial unmethylated CpG DNA
NOD-1 and NOD-2 -> bacterial peptidoglycan
NLRP3 -> changes in cytosol and forms inflammasome

BBS2001 Threats and Defence Mechanisms

What do TLR4, TLR5, TLR9, NOD-1 and NOD-2 and NLRP3 recognise respectively?

TLR4 and NLRP3-> LPS TLR5 -> bacterial flagella TLR9 -> bacterial unmethylated CpG DNA NOD-1 and NOD-2 -> bacterial peptidoglycan NLRP3 -> changes in cytosol and forms inflammasome

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