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BBS2001 Threats and Defence Mechanisms
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Question:
What is the function of regulatory T cells and how is this done?
Author: Mirte SchattorieAnswer:
To suppress the immune response to not harm commensal bacteria this is done by; - production of cytokines that inhibit activation of lymphocytes - expressing CTLA-4 which block B7 molecules -> APCs cannot costimulate the T cells and T cells will not be activated - binding to T cell growth factor, reducing the availability for the T cells
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