How do effector T cells migrate to the site of infection?

1. high levels of E- and P-selectin and integrins LFA-1 and VLA-4 are expressed on the T cell 2. the cytokine produced by the innate response (TNF, IL-1) act on endothelial cells to increase expression of E- and P-selectin and integrin ligands 3. rolling adhesion occurs 4. T cells express receptors for chemokines produced by the infection, this increases binding affinity and causes firm adhesion to the endothelium 5. T cells enter the tissue through the junctions 6. T cells follow chemokines to infection