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BBS2001 Threats and Defence Mechanisms
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Question:
What are the different parts of an immunoglobulin molecules?
Author: Mirte SchattorieAnswer:
They have two heavy and two light chains, each chain containing a variable and a constant region. this is all connected by disulfide bonds there are three functional parts; - fab (fragment antigen binding) -> the entire light chain attached to the V and part of the C domain of the heavy chain (recognition of antigens) - fc (fragment crystalline) -> remaining part of the heavy chain (effector function of the antibody) -hinge region -> flexible region
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