Question:
Production of viral particles CAN ONLY OCCUR IN HIGHLY DIFFERENTIATED KARATINOCYTES. The process of virus replication alters the character of the epidermis resulting in cutaneous or mucosal warts, it penetrates the basal layer and eventually is released at the surface; the modes of replication are?
Author: SageAnswer:
STABLE replication of episomal genomes in BASAL CELLs RUNAWAY/VEGITATIVE replication in DIFFERENTIATED CELLS to generate progeny virus. note: viral genes are not activated until infected karatinocyte leaves basal layer.
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