Hypoadrenal crisis

Hypotension, Hypoglycaemia, Hyponatraemia, Hyperkalaemia, Sever dehydration, Death if untreated Treatment: Acute presentation is a medical emergency, long term treatment necessary, Hydrocortisone 20-30mg daily (ammunocortisol replacement), Fludrocortisone 50-300ug daily Confirmatory tests: • 0900 cortisol (peak cortisol) should be 300 • Short synacthen test • ACTH • Plasma renin • Adrenal antibodies