3. An excessive blood group soluble substance causes what group of discrepancy in ABO typing. How can it be resolved

- Too much levels can cause a rare Group II ABO discrepancy. Excess amounts of BGSS substances will neutralize the reagent anti-A or anti-B, leaving no unbound antibody to react with the patient cells and yields a false-negative or weak reaction in the forward grouping. It would be alleviated through washing the patient cells free of the BGSS substances with saline, resulting in correlating forward and reverse groupings