Degradation by autophagy – who decides? (Bacterial recognition)

1.Induce starvation – take nutrients. 2.Tol-like receptors can recognise bacteria and initiate autophagy. 3.Xenophagy initiated by SLRs or other mechanisms. SLRs share common motifs:Common LIR/CLIR motif – LC3-interacting region, UBx motifs, e.g. UBAN –ubiquitin binding domains.