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MCB L17-18

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Question:

How does Myosin V travel (hand over hand)

Author: Alex Rapai



Answer:

Researchers managed to attach a fluorescent probe to only one of the two myosin heads. This revealed that Myosin V moves by taking 72nm steps. Indeed this is almost exactly the distance between the successive helical turns on the actin filament so Myosin V walks down only one side of the actin filament. This is precisely the properties you would expect for a good processive motor.


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