Question:
How does protein A contribute to the virulence of staph aureus?
Author: H KAnswer:
IgG antibodies have an Fc portion and a Fab portion (attaches to the antigen). The Fc portion is important in the phagocytosis mediated by antibody opsonization. However, if the protein A is attached to the Fc portion, it will replace the phagocyte and help the Staphylococcus Aureus avoid phagocytosis and its destruction by phagocytic cells.
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H K