Apixaban: -Class -Side effects -Monitoring -Factors affecting dose

- Anticoagulant (DOAC) - Increased bleeding risk - No regular INR monitoring required -Must monitor: general compliance- short half life (if stopped for a few days, they are no longer anticoagulated), any problematic signs/symptoms, age, weight & renal function (CrCl) - Dosing depends on renal function (must use Creatinine clereance & not eGFR) -Dose is reduced if 2 of the following 3 apply: (serum creatinine >133micromol/litre, age>80, body weight <60kg)