Enalapril: -Class -Side effects -Renal -Hyperkalemia -Monitoring -Preganancy

-ACE inhibitor -Angioedema (swelling), may be accompanied by a rash -Can happen at start/during treatment -Patients that happemn to have had ACEI induced angioedema shouldnt be given this class of drug again (high risk of recurrence) -ACEI induced angioedma is due to excessive accumlation of bradykinin -Renal Impairment First-Dose hypotension (especially with concomittant diuretics) could take before bed -Hyperkaelamia -Persisent dry cough -Can cause renal toxcity be reno-protective -Will exspcet a small decline in renal function/eGFR when starting ACEI -There shouldnt be a massive decline- if there is it means it is contra-indicated -If they have bilateral renal artery stenosis (narrowed renal arterires-usally caused by atherosclerosis), ACEI reduce/abolish glomerular filtration-likley to cause renal failure -If they have CVD & known atherosclerosis or suspected/known renovascular disease- try to avoid ACEI in these patients