Furosemide: -Class -Pathophysiology -Renal -Monitoring -STOPP Criteria (In older people) -Hypokaelamia -Prostate

-Loop diuretic -By interacting with ascending limb of the loop of henle, it inc excretion of sodium (can cause hyponatraemia- presents with confusion) + water -Rapid onset of action (IV 5 mins, orally 1-2 hours) -Duration of action= 4-6 hours – as they will be urinating a lot, can be problematic if they want to go out→ COUNSEL them on this -Inc risk of renal impairment→ they reduce blood volume- reduces blood flow to the kidneys- reduces eGFR → need to monitor renal function + electrolyte abnormalities -Need to monitor renal function, electrolytes and blood pressure (as blood vol is reduced- causes reduction in BP) regularly -If indication unclear, it needs to be reviewed (as it may be inappropriate): -It is NOT 1st line for hypertension (safer alternatives available) -For hypertension with concurrent urinary incontinence- may exacerbate incontinence For ankle oedema, but there’s no evidence of HF, liver failure, nephrotic syndrome or renal failure- safer alternatives available -Hypokaelamia (Loop diuretics cause- dangerous in patients with CVD- or if on cariac glycosides- digoxin- toxcitiy