Describe the DNA replication process in vivo (living cells)

DNA is unwound and hydrogen bonds between bases are broken to form two template strands The enzyme DNA polymerase needs primers to start replication. Primer allows DNA polymerase to add DNA nucleotides using complementary base pairing to the 3' deoxyribose end of the primer DNA polymerase can only add nucleotides in one direction (3' - 5') resulting in the leading strand being replicated continuously and the lagging strand being replicated in fragments. The fragments of DNA on the lagging strand are joined together by the enzyme ligase