Adverse Effects of NSAIDs

• CNS: headaches, tinnitus, dizziness • CV: fluid retention hypertension, edema, and rarely CHF • GI: abdominal pain, dysplasia, N&V, ulcers or bleeding • Hematologic: rare thrombocytopenia, neutropenia, aplastic anemia • Hepatic: abnormal liver function tests and rare liver failure • Pulmonary: asthma • Rashes: all types, pruritus • Renal: renal insufficiency, renal failure, hyperkalemia, proteinuria