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Endocrinology

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Question:

How is the physiology of the hypothalamic-hypophyseal axis?

Author: H K



Answer:

For hypothalamus, there is a pulsatile stable secretion of GnRH every 90 mins throughout the cycle, but difference is in gonadotrophic cells receptors according to the phase we are in (follicular or luteal) and may be influenced by activating factors (VIP and NE) or inhibiting ones (dopa, endorphins, serotonin, GABA) For pituitary LH and FSH prodocution depends on the hormonal phase we are in (Luteal LH, Follicular FSH) There are hormones controlling it (Sexual hormones, monamines, and most importantly Prolactin)


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H K
H K