Question:
What are the etiologies of primary hypermineralocorticism?
Author: H KAnswer:
Adenoma producing aldosterone (APA) (~ 65%) Bilateral Adrenal hyperplasia (BAH) (30-40%): lead to overproduction of aldosterone Unilateral adrenal hyperplasia (UAH) Glucocorticoid remediable hyperaldosteronism (GRA) (Known by aldosterone synthase hyperactivity that is ACTH sensetive; steroid therapy blocks ACTH and thus aldosterone production) Corticoadrenaloma: malignant tumor
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H K