MBS1002 Biomedical Approaches: how are single-stranded breaks, double-stranded breaks, DNA adducts (crosslinks and oxidized bases) and mutations repaired?

Question

how are single-stranded breaks, double-stranded breaks, DNA adducts (crosslinks and oxidized bases) and mutations repaired?

Mirte Schattorie · Accepted Answer

SSBs: base excision repair (BER)
DSBs: non homologous endjoining (NHEJ) or homologous recombination (HR)
DNA adducts, crosslinks and oxidized bases: nucleotide excision repair (NER)
mutation: mismatch repair (MMR)

MBS1002 Biomedical Approaches

How are single-stranded breaks, double-stranded breaks, DNA adducts (crosslinks and oxidized bases) and mutations repaired?

SSBs: base excision repair (BER) DSBs: non homologous endjoining (NHEJ) or homologous recombination (HR) DNA adducts, crosslinks and oxidized bases: nucleotide excision repair (NER) mutation: mismatch repair (MMR)

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