What are the clinical manifestations of asthma?

Typical: wheeze, SoB, chest tight, cough Variable symptoms (time and intensity, triggered by exercise/allergen/laugh..., can worsen with infection) can be confused with acute viral tracheobronchitis (resolves after 6 weeks), or COPD. hypersensitivity has 2 phases, immediate one with allergen , and late one after 6 hours for example 10% don't have SoB (more tolerant). Symptoms more episodic than COPD and prolonged remission period typically, more in children (COPD in elderly), seasonal (Unlike COPD) Some pt have overlap syndrome (smokers with asthma)