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Pneumology

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Question:

How is theophylline used in asthma management?

Author: H K



Answer:

Adjunct for pt with failed corticosteroid treatment, weak bronchodilation and anti-inflammatory effect, inhibit phosphodiesterase increasing cAMP. We should monitor blood levels to avoid toxicity (especially elderly - GI side effects 20-30 microg/ml, cardiac arrhythmias, seizures, blood glucose 8-15 therapeutic)


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Author

H K
H K