What are drug induced pulmonary disorders?

Non-specific spectrum of symptoms, exclusion dx. Lung is the only organ to recieve the whole circulation, so all drugs affect it. Rxns can affect pleura, airways, vessels, muscles Theories (cytotoxic effect on endothelia, direct oxidative injury, deposit of phospholipid particularity in macrophage, immune-mediated injury (SLE, hypersensitivity) Injuries include (pneumonia, fibrosis, hypersensitivity, edema, bronchospasm, pulmonary HTN